Genetic Science Learning Center. "What is a Stem Cell?." Learn.Genetics 13 November 2008 http://learn.genetics.utah.edu/content/tech/stemcells/scintro/ 1.What is a stem cell? TD 2.A cell in the body whose job is not yet determined TD 3.Every cell in body “stems” from these cells (hence the name) TD 4.Wait for signals to tell them what to become TD 5.Until they get signal they slowly sit and divide TD 6.Once signal comes they differentiate (gradually change into the decided cell) TD 7.Signal causes certain genes to turn on TD 8.Signal also tells the cell to make certain proteins TD 9.The proteins cause the cell to look like and act like the new cell TD 10.The differentiation process helps cells to specialize to their special jobs TD 11.Nerve cells are made early on before birth TD 12.Nerve cells relay information from and within the brain TD 13.Skin cells are being constantly made throughout life TD 14.Bone cells are also constantly growing and fixing themselves TD 15.Red blood cells are also a product of stem cells TD 16.The red blood cells are made within the bone marrow TD 17.Stem cells become myoblast and then multiply TD 18.Large groups of myoblasts come together to form muscles TD 19.Embryonic stem cells are totipotent (they can become any type of cell) TD 20.Blastocyst embryonic stem cells are pluripotent (can become almost any cell) TD 21.They don’t have human characteristics yet TD 22.Fetal stem cells – 8 weeks after conception TD 23.Fetal stem cells are also pluripotent TD 24.Umbilical cord stem cells are multipotent (limited number of cells they can become) TD 25.Adult stem cells are the developed-matured cells found in tissues TD
Scolari , S.. What Is Stem Cell Research?. 2003 wisegeek.com. 11/13/08 <http://www.wisegeek.com/what-is-stem-cell-research.htm>. 26.Taking basic human cells and turning them into any other of the basic 220 cells in body-JS 27.Meant to find cures to major diseases-JS 28.Some against it as it may come to cloning-JS 29.Viewed negative as destroys embryo-JS 30.Adult cells can be used as well-JS 31.Some countries have legalized-JS
34.Since 1997 with clone sheep scientist striving to do same to human-JS 35.Some clones left dead-JS 36.Most clones left with physical and genetic problems-JS 37.Clones have respiratory issues-JS 38.America outlawed human cloning-JS 39.Thought that cloning human impossible-JS 40.Too many risks to clone human at time-JS
41.Embryonic stem cell can go into all tissues in the body KF 42.adult cells cam multiply and hold all origins of tissue from where it can from KF 43.scientists believe that this can cure diseases that affected 128 million people KF 44.to create a cell you need a stem line KF 45.stem line- a mass of cells sharing genetic characteristics KF
46.offer a lot of hope because they can grow into any kind of cell KF 47.stem cells can replace dead cells from cancer KF 48.billions of dollars are being put in this field KF 49.3 kinds – adult, cord, and embryonic KF 50.adult cells are extracted from either bone marrow or peripheral system KF 51.if extracted from bone marrow possibility of bone being destroyed KF 52.if extracted from peripheral system no bone will be destroyed but it will take longer KF 53.adult stem cell is the best out of the three KF 54.cord cells are 2nd best KF 55.cord cells are for families that planned ahead KF 56.cord cells are extracted during pregnancy and stored in cryogenic cell banks KF 57.cord cells are mainly used for the new born KF 58.the closer the person is to your blood line the better KF 59.storage process is like blood bank KF 60.embryonic cells are extracted from an embryo before it differentiates KF 61.at this stage it is known as blastocyst KF 62.there are about 100 cells in the blastocyst KF 63.grown in cultures were they can multiply every 2-3 days KF 64.this cell requires a dead human KF 65.some believe that it is murder KF
Stein, Constance. "Stem cells." Gale Encyclopedia of Science. Ed. K. Lee Lerner and Brenda Wilmoth Lerner. 4th ed. Detroit: Gale Group, 2008. StudentResourceCenter- Gold. Gale. FREDERICK COUNTY PUBLIC LIBRARY. 13 Nov. 2008 <http://find.galegroup.com/srcx/infomark.do? &contentSet=GSRC &type=retrieve &tabID=T001 &prodId=SRC-1 &docId=EJ2644042198 &source=gale &srcprod=SRCG &userGroupName=fred14595 &version=1.0>. www.galenet.galegroup.com
66.Stem cells replace dead or damaged cells-AH 67.revolutionizes treatments for diseases -AH 68.Stems cells multiply-AH 69.Are a “repair system”-AH 70.They can choose to become any cell they want-AH 71.They can heal wounds without scarring -AH 72.Is like a fountain of youth-AH
76.What is the goal of stem cell research? TD 77.Stem cells form the basic building materials for the human body TD 78.They are the perfect choice for restoring tissues that have been damaged or destroyed due to injury or disease TD 79.The goal of any stem cell research is to repair tissue that cant fix itself TD 80.One possibility is to transplant stem cells directly into the damaged area and directing them to grow new healthy tissue TD 81.Also possible to coax stem cells already in the body to work overtime and produce new tissue TD 82.Stem cell transplants have been the best method to date TD
Genetic Science Learning Center. "Stem Cell Therapies Today." Learn.Genetics 14 November 2008 http://learn.genetics.utah.edu/content/tech/stemcells/sctoday 83.Some therapies are used to treat diseases already TD 84.Adult stem cell transplant: bone marrow stem cells TD 85.Adult stem cell transplant: peripheral blood stem cells TD 86.Umbilical cord stem cell transplant TD 87.The bone marrow transplant is used to treat leukemia and other types of cancer, as well as various types of blood disorders TD 88.Small number of stem cells reside in the blood stream TD 89.These cells can also be use like the bone marrow in helping leukemia and various blood disorders TD 90.They are very sparse so collecting these cells is a challenge TD 91.Umbilical cord blood is very potent in stem cells TD 92.They are collected and kept in cold storage TD 93.They can be used like the bone marrow transplant TD Stem Cell Basics: What are the unique properties of all stem cells?Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2006 http://stemcells.nih.gov/info/basics/basics2 94.all stem cells have 3 general properties KF 95.capable of dividing KF 96.they are unspecialized KF 97.They can give rise to specialized cell types. KF 98.Embryonic cells can proliferate for a year or more in a lab. Adults cant
stem cell research can lead to stopping cancer KF 99.stem cells can go into almost any human blood stream KF 100.capable of a long term self-renewal KF 101.How are embryonic stem cells stimulated to differentiate? 102.it took 20 years to figure out how human embryo cells work KF 103.When unspecialized stem cells give rise to specialized cells, the process is called differentiation KF 104.internal signals are controlled by cell genes KF
Winfield, Julian. Stemaid: the future of medicine. 2007 www.stemaid.com. November 14, 2008 http://www.stemaid.com/page.php?2 105.can cure a lot KF 106.Acute and Chronic Stroke KF 107.parkinsons disease KF 108.multiple sclerosis KF 109.Autism KF 110.Huntington's disease KF 111.Migraine Headaches KF 112.Epilepsy KF 113.Blood Cancer KF 114.Organ/Tissue Cancers KF 115.Leukemia’s KF 116.Chemo Rescue KF 117.AIDS (advanced) KF 118.Hepatitis C KF 119.Hepatitis B KF 120.Cirrhosis KF 121.Macular Degeneration KF 122.Glaucoma KF 123.Rheumatoid Arthritis KF 124.Lupus KF 125.Diabetes KF 126.Addison's Disease KF 127.Myocardial Infarction KF 128.Bronchial Asthma KF 129.Injury and infection related hearing loss KF 130.Common Variable Immunodeficiency KF 131.Kidney conditions KF 132.Accelerated recovery from Accident or Surgery KF 133.Vision loss KF 134.takes about 3-6 months to complete KF 135.everyone heals different KF 136.it is better if you don’t take drugs or use alcohol while in healing process KF 137.no negative side effects KF 138.stem cells can reproduce into any of the 220 different types of cells in the human body KF 139.they have stem cell therapy KF
stem cell research pros and cons. 2006 www.stemcellresearchfacts.com. 11/14/08 <http://www.stemcellresearchfacts.com/pros_cons.html>. 140.destruction of human life in creation JS 141.adults might be harder to “reprogram” cells JS 142.nothing bad happens to donor JS
Stem Cell Basics: Introduction . In Stem Cell Information [World Wide Web site]. Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2006 [cited Friday, November 14, 2008] Available at <http://stemcells.nih.gov/info/basics/basics1>
143.can be made into needed cells JS 144.not focused cells JS 145.regenerate though division JS 146.help make test tube babies JS
Stem Cell Basics: What are the unique properties of all stem cells? . In Stem Cell Information [World Wide Web site]. Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2006 [cited Friday, November 14, 2008] Available at http://stemcells.nih.gov/info/basics/basics2 147.has no structure as to tissue or muscle JS 148.stem cells can replicate JS 149.stem cells can regenerate JS 150.stem cells similar to cancer JS
How stuff works. "Stem Cells." Stem Cells. 1998-2008. How Stuff works. 13-11-2008 http://www.howstuffworks.com/search.php?terms=Stem+Cell. www.science.howstuffworks.com 151.Can turn into 220 different kinds of cells-AH 152.Capability of self-renewal -AH 153.Therapeutic cloning-AH 154.Uses Fertilized embryos from fertility programs-AH 155.Stem cells are they inner cells to the blastocyst-AH 156.Called Cell-based therapy-Ah
157.Common issues surrounding stem cell research 158.How far should researchers take stem cell technologies? TD 159.Should we do something for the sake of doing it? TD 160.Should the government fund the research? TD 161.Should there be laws governing stem cell research? TD 162.Do embryonic stem cells represent human life? TD 163.– Should the fetus have rights? 164.– Who should be able to make the choice? 165.Should frozen embryos created through vitro fertilizations be used to create stem cells? TD
166.The decision, characterized at the time as perhaps the most important of Bush's presidency KF 167.President Bush has long opposed embryonic stem cell research on ideological grounds KF 168.President George W. Bush vetoed the bill on June 20, 2007 KF
Genetic Science Learning Center. "What is a Stem Cell?." Learn.Genetics 13 November 2008 http://learn.genetics.utah.edu/content/tech/stemcells/scintro/
1. What is a stem cell? TD
2. A cell in the body whose job is not yet determined TD
3. Every cell in body “stems” from these cells (hence the name) TD
4. Wait for signals to tell them what to become TD
5. Until they get signal they slowly sit and divide TD
6. Once signal comes they differentiate (gradually change into the decided cell) TD
7. Signal causes certain genes to turn on TD
8. Signal also tells the cell to make certain proteins TD
9. The proteins cause the cell to look like and act like the new cell TD
10. The differentiation process helps cells to specialize to their special jobs TD
11. Nerve cells are made early on before birth TD
12. Nerve cells relay information from and within the brain TD
13. Skin cells are being constantly made throughout life TD
14. Bone cells are also constantly growing and fixing themselves TD
15. Red blood cells are also a product of stem cells TD
16. The red blood cells are made within the bone marrow TD
17. Stem cells become myoblast and then multiply TD
18. Large groups of myoblasts come together to form muscles TD
19. Embryonic stem cells are totipotent (they can become any type of cell) TD
20. Blastocyst embryonic stem cells are pluripotent (can become almost any cell) TD
21. They don’t have human characteristics yet TD
22. Fetal stem cells – 8 weeks after conception TD
23. Fetal stem cells are also pluripotent TD
24. Umbilical cord stem cells are multipotent (limited number of cells they can become) TD
25. Adult stem cells are the developed-matured cells found in tissues TD
Scolari , S.. What Is Stem Cell Research?. 2003 wisegeek.com. 11/13/08 <http://www.wisegeek.com/what-is-stem-cell-research.htm>.
26. Taking basic human cells and turning them into any other of the basic 220 cells in body-JS
27. Meant to find cures to major diseases-JS
28. Some against it as it may come to cloning-JS
29. Viewed negative as destroys embryo-JS
30. Adult cells can be used as well-JS
31. Some countries have legalized-JS
"Babies from bone marrow.(data)(Report)(Brief article)." Discover, July 2007 v28 i7 p17(1). Science Resource Center. Gale. 13 November 2008 <http://galenet.galegroup.com/servlet/SciRC?ste=1&docNum=A164721636>
32. Discovery made using bone marrow to make a baby-JS
33. Though thought not able to work-JS
Detroit: Thomson Gale, 2007. Science Resource Center. Gale. 13 November 2008 <http://galenet.galegroup.com/servlet/SciRC?ste=1&docNum=CV2643510023 >
34. Since 1997 with clone sheep scientist striving to do same to human-JS
35. Some clones left dead-JS
36. Most clones left with physical and genetic problems-JS
37. Clones have respiratory issues-JS
38. America outlawed human cloning-JS
39. Thought that cloning human impossible-JS
40. Too many risks to clone human at time-JS
Fact Sheet: Embryonic Stem Cell Research. August 2001 www.whitehouse.gov. November 13 2008 http://www.whitehouse.gov/news/releases/2001/08/20010809-1.html.
41. Embryonic stem cell can go into all tissues in the body KF
42. adult cells cam multiply and hold all origins of tissue from where it can from KF
43. scientists believe that this can cure diseases that affected 128 million people KF
44. to create a cell you need a stem line KF
45. stem line- a mass of cells sharing genetic characteristics KF
Pros And Cons Of Stem Cell Research. 2008 www.allaboutpopularissues.org. November 13 2008 http://www.allaboutpopularissues.org/pros-and-cons-of-stem-cell-research.htm.
46. offer a lot of hope because they can grow into any kind of cell KF
47. stem cells can replace dead cells from cancer KF
48. billions of dollars are being put in this field KF
49. 3 kinds – adult, cord, and embryonic KF
50. adult cells are extracted from either bone marrow or peripheral system KF
51. if extracted from bone marrow possibility of bone being destroyed KF
52. if extracted from peripheral system no bone will be destroyed but it will take longer KF
53. adult stem cell is the best out of the three KF
54. cord cells are 2nd best KF
55. cord cells are for families that planned ahead KF
56. cord cells are extracted during pregnancy and stored in cryogenic cell banks KF
57. cord cells are mainly used for the new born KF
58. the closer the person is to your blood line the better KF
59. storage process is like blood bank KF
60. embryonic cells are extracted from an embryo before it differentiates KF
61. at this stage it is known as blastocyst KF
62. there are about 100 cells in the blastocyst KF
63. grown in cultures were they can multiply every 2-3 days KF
64. this cell requires a dead human KF
65. some believe that it is murder KF
Stein, Constance. "Stem cells." Gale Encyclopedia of Science. Ed. K. Lee Lerner and Brenda Wilmoth Lerner. 4th ed. Detroit: Gale Group, 2008. Student Resource Center - Gold. Gale. FREDERICK COUNTY PUBLIC LIBRARY. 13 Nov. 2008 <http://find.galegroup.com/srcx/infomark.do? &contentSet=GSRC &type=retrieve &tabID=T001 &prodId=SRC-1 &docId=EJ2644042198 &source=gale &srcprod=SRCG &userGroupName=fred14595 &version=1.0>. www.galenet.galegroup.com
66. Stem cells replace dead or damaged cells-AH
67. revolutionizes treatments for diseases -AH
68. Stems cells multiply-AH
69. Are a “repair system”-AH
70. They can choose to become any cell they want-AH
71. They can heal wounds without scarring -AH
72. Is like a fountain of youth-AH
Stem cell Research-Pros and Cons. 2008 www.experiment-resources.com. 13-11-2008 <http://www.experiment-resources.com/stem-cell-pros-and-cons.html>.
73. Stem cells are crucial for the development to an organism-AH
74. Grown in laboratories-AH
75. Obtained by killing the human embryo-AH
Genetic Science Learning Center. "What is the Goal of Stem Cell Research?." Learn.Genetics 14 November 2008 http://learn.genetics.utah.edu/content/tech/stemcells/scresearch/
76. What is the goal of stem cell research? TD
77. Stem cells form the basic building materials for the human body TD
78. They are the perfect choice for restoring tissues that have been damaged or destroyed due to injury or disease TD
79. The goal of any stem cell research is to repair tissue that cant fix itself TD
80. One possibility is to transplant stem cells directly into the damaged area and directing them to grow new healthy tissue TD
81. Also possible to coax stem cells already in the body to work overtime and produce new tissue TD
82. Stem cell transplants have been the best method to date TD
Genetic Science Learning Center. "Stem Cell Therapies Today." Learn.Genetics 14 November 2008 http://learn.genetics.utah.edu/content/tech/stemcells/sctoday
83. Some therapies are used to treat diseases already TD
84. Adult stem cell transplant: bone marrow stem cells TD
85. Adult stem cell transplant: peripheral blood stem cells TD
86. Umbilical cord stem cell transplant TD
87. The bone marrow transplant is used to treat leukemia and other types of cancer, as well as various types of blood disorders TD
88. Small number of stem cells reside in the blood stream TD
89. These cells can also be use like the bone marrow in helping leukemia and various blood disorders TD
90. They are very sparse so collecting these cells is a challenge TD
91. Umbilical cord blood is very potent in stem cells TD
92. They are collected and kept in cold storage TD
93. They can be used like the bone marrow transplant TD
Stem Cell Basics: What are the unique properties of all stem cells?Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2006 http://stemcells.nih.gov/info/basics/basics2
94. all stem cells have 3 general properties KF
95. capable of dividing KF
96. they are unspecialized KF
97. They can give rise to specialized cell types. KF
98. Embryonic cells can proliferate for a year or more in a lab. Adults cant
stem cell research can lead to stopping cancer KF
99. stem cells can go into almost any human blood stream KF
100. capable of a long term self-renewal KF
101. How are embryonic stem cells stimulated to differentiate?
102. it took 20 years to figure out how human embryo cells work KF
103. When unspecialized stem cells give rise to specialized cells, the process is called differentiation KF
104. internal signals are controlled by cell genes KF
Winfield, Julian. Stemaid: the future of medicine. 2007 www.stemaid.com. November 14, 2008 http://www.stemaid.com/page.php?2
105. can cure a lot KF
106. Acute and Chronic Stroke KF
107. parkinsons disease KF
108. multiple sclerosis KF
109. Autism KF
110. Huntington's disease KF
111. Migraine Headaches KF
112. Epilepsy KF
113. Blood Cancer KF
114. Organ/Tissue Cancers KF
115. Leukemia’s KF
116. Chemo Rescue KF
117. AIDS (advanced) KF
118. Hepatitis C KF
119. Hepatitis B KF
120. Cirrhosis KF
121. Macular Degeneration KF
122. Glaucoma KF
123. Rheumatoid Arthritis KF
124. Lupus KF
125. Diabetes KF
126. Addison's Disease KF
127. Myocardial Infarction KF
128. Bronchial Asthma KF
129. Injury and infection related hearing loss KF
130. Common Variable Immunodeficiency KF
131. Kidney conditions KF
132. Accelerated recovery from Accident or Surgery KF
133. Vision loss KF
134. takes about 3-6 months to complete KF
135. everyone heals different KF
136. it is better if you don’t take drugs or use alcohol while in healing process KF
137. no negative side effects KF
138. stem cells can reproduce into any of the 220 different types of cells in the human body KF
139. they have stem cell therapy KF
stem cell research pros and cons. 2006 www.stemcellresearchfacts.com. 11/14/08 <http://www.stemcellresearchfacts.com/pros_cons.html>.
140. destruction of human life in creation JS
141. adults might be harder to “reprogram” cells JS
142. nothing bad happens to donor JS
Stem Cell Basics: Introduction . In Stem Cell Information [World Wide Web site]. Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2006 [cited Friday, November 14, 2008] Available at <http://stemcells.nih.gov/info/basics/basics1>
143. can be made into needed cells JS
144. not focused cells JS
145. regenerate though division JS
146. help make test tube babies JS
Stem Cell Basics: What are the unique properties of all stem cells? . In Stem Cell Information [World Wide Web site]. Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2006 [cited Friday, November 14, 2008] Available at http://stemcells.nih.gov/info/basics/basics2
147. has no structure as to tissue or muscle JS
148. stem cells can replicate JS
149. stem cells can regenerate JS
150. stem cells similar to cancer JS
How stuff works. "Stem Cells." Stem Cells. 1998-2008. How Stuff works. 13-11-2008 http://www.howstuffworks.com/search.php?terms=Stem+Cell.
www.science.howstuffworks.com
151. Can turn into 220 different kinds of cells-AH
152. Capability of self-renewal -AH
153. Therapeutic cloning-AH
154. Uses Fertilized embryos from fertility programs-AH
155. Stem cells are they inner cells to the blastocyst-AH
156. Called Cell-based therapy-Ah
Genetic Science Learning Center. "What Are Some Issues In Stem Cell Research?." Learn.Genetics 14 November 2008 http://learn.genetics.utah.edu/content/tech/stemcells/scissues/
157. Common issues surrounding stem cell research
158. How far should researchers take stem cell technologies? TD
159. Should we do something for the sake of doing it? TD
160. Should the government fund the research? TD
161. Should there be laws governing stem cell research? TD
162. Do embryonic stem cells represent human life? TD
163. – Should the fetus have rights?
164. – Who should be able to make the choice?
165. Should frozen embryos created through vitro fertilizations be used to create stem cells? TD
White, Deborah . Pros & Cons of Embryonic Stem Cell Research. 2007 www.about.com. November 14 2008 http://usliberals.about.com/od/stemcellresearch/i/StemCell1.htm
166. The decision, characterized at the time as perhaps the most important of Bush's presidency KF
167. President Bush has long opposed embryonic stem cell research on ideological grounds KF
168. President George W. Bush vetoed the bill on June 20, 2007 KF
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http://www.molecularstation.com/molecular-biology-images/data/504/Blastocyst.jpg
-Blastocyst
http://www1.imperial.ac.uk/resources/79397A97-0B6D-4797-8FFF-DE3EB8B22030/
-fetal
http://www.leukemia-web.org/images/cells.jpg
-Umbilical Cord
http://dodarivka.com/news4/images/stories/New_Source_Of_Multipotent_Adult_Stem_Cells_Discovered_In_Human_Hair_Follicles.jpg-adult